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Case Study- Covid-19 in Critically Ill Patients in the Seattle Region

Covid-19 in Critically Ill Patients in the Seattle Region — Case Series

List of authors.Pavan K. Bhatraju, M.D., Bijan J. Ghassemieh, M.D., Michelle Nichols, M.D., Richard Kim, M.D., Keith R. Jerome, M.D., Arun K. Nalla, Ph.D., Alexander L. Greninger, M.D., Sudhakar Pipavath, M.D., Mark M. Wurfel, M.D., Ph.D., Laura Evans, M.D., Patricia M. Kritek, M.D., T. Eoin West, M.D., M.P.H., Andrew Luks, M.D., Anthony Gerbino, M.D., Chris R. Dale, M.D., Jason D. Goldman, M.D., Shane O’Mahony, M.D., and Carmen Mikacenic, M.D.

Identified patients from nine Seattle-area hospitals who were admitted to the intensive care unit (ICU) with confirmed infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Clinical data were obtained through review of medical records. The data reported here are those available through March 23, 2020. Each patient had at least 14 days of follow-up


During the first 3 weeks of the Covid-19 outbreak in the Seattle area, the most common reasons for admission to the ICU were hypoxemic respiratory failure leading to mechanical ventilation, hypotension requiring vasopressor treatment, or both. Mortality among these critically ill patients was high. (Funded by the National Institutes of Health.)

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