Info
Caused by a virus thought to be Droplet Transmission but also uncertainty as to whether it is Airborne. (JAMA, WHO)
Incubation is thought to be 2-14 days after exposure (average is 5 days) (WHO)
Current evidence supports a patient having immunity once recovered - presence of antibodies (CDC)
One estimate suggests 3% of all COVID-19 pts require intubation, with about a 50% survival chance on the ventilator (Meng, et. al), some report mortality as high as 81% (Weis, et. al)
Severe (dyspnea, hypoxia, > 50% lung involvement) occurs around 14% of cases, Critical (resp failure, shock, multi-system organ failure) occurs around 5% of cases (CDC) Overall case fatality is around 2.3%, but closer to 50% in those with severe COVID-19. ICU mortality ranges from 39%-72% (CDC)
CT scan is more helpful than CXR, but either may indicate bilateral, peripheral ground-glass opacities (CDC, Pan et. al )
While more rare in children, often presents initially as a mild flu-like illness, more likely to be mild symptoms (Guo, et. al, Wei, et. al)
Avoid PFTs unless critical for immediate treatment, then use only absolutely necessary tests (IPC, ATS)
Read More: https://www.oakesacademy.com/public/Coronavirus-Clinical-Collaboration.cfm
Reference & source Information : https://www.oakesacademy.com
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